Rosuvastatin-warfarin drug interaction.

we estimate that there are more than 100000 patients presently on statin treatment, and that about 10% of these patients will also be on long-term warfarin therapy. I believe your Editorial was correct in highlighting the issue of safety, and to suggest that “physicians must tell their patients the truth about rosuvastatin”. However, I would add that physicians themselves should be informed of the real risk of a clinically significant interaction between rosuvastatin and warfarin. Such a combination should be avoided in my view—alternative statin drugs can be safely co-administered. Michael Barry